Kokomo Tribune; Kokomo, Indiana

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March 4, 2014

4 women with new wombs are trying to get pregnant

LONDON (AP) — A Swedish doctor says four women who received transplanted wombs have had embryos transferred into them in an attempt to get pregnant.

He would not say on Monday whether any of the women had succeeded. In all, nine women in Sweden have received new wombs since 2012, but two had to have them removed because of complications.

The women received wombs donated by their mothers or other close relatives in an experimental procedure designed to test whether it's possible to transfer a uterus so a woman can give birth to her own biological child. The women had in vitro fertilization before the transplants, using their own eggs to make embryos.

"We have already begun transferring embryos into four of the women and plan to make attempts with the others when they are ready," said Dr. Mats Brannstrom, a professor of obstetrics and gynecology at the University of Goteburg, who is leading the research.

Brannstrom predicted that three or four of the seven women might successfully give birth.

"One or two more will perhaps get pregnant and miscarry, and one or two won't be able to get pregnant," he said.

There have been two previous attempts to transplant a womb — in Turkey and Saudi Arabia — but both failed to produce babies. Doctors in Britain and Hungary also are planning similar operations, but using wombs from women who had just died.

Brannstrom said any woman in the study who does get pregnant will be on a low dose of drugs to keep from rejecting the transplanted womb and will be monitored as a high-risk pregnancy.

The transplants are intended to benefit women unable to have children because they lost a uterus to cancer or were born without one.

Some doctors said women who got pregnant with a new uterus would have to be watched carefully for how the womb progresses throughout pregnancy.

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