Kokomo Tribune; Kokomo, Indiana

Bonus content

March 5, 2014

Studies show big promise for HIV prevention drug

(Continued)

The monkeys who got the fake treatment were readily infected "but the animals that received the long-acting drug remained protected," said study leader Gerardo Garcia-Lerma of the CDC.

The results mirror what was seen in the CDC's early research in monkeys on Truvada, the pill that's available for HIV prevention now.

In the second study, Chasity Andrews and others at the Aaron Diamond AIDS Research Center at Rockefeller University in New York gave eight monkeys two shots of the drug, four weeks apart, and dummy shots to eight others. The animals were exposed to the virus weekly for eight weeks. Again, all animals given the fake treatment were quickly infected and those on the drug were all protected.

To see how long a single shot would last, they did a second study. The single shot protected 12 monkeys for about 10 weeks on average.

The dose used in a single shot corresponded to what people would get from a shot every three months, researchers said.

"This is really promising," said Dr. Judith Currier, an infectious disease specialist at the University of California, Los Angeles. The research "supports moving this forward" into human testing, she said.

Currier is on the program committee for the meeting in Boston where the studies were presented — the Conference on Retroviruses and Opportunistic Infections. The New York study also was published online by the journal Science.

Grant said the long-acting drug is chemically similar to certain AIDS medicines sold now that are "extremely safe, well tolerated and extremely potent." A mid-stage trial testing the long-acting shots in people as a treatment, not a prevention, is already underway, he said.

------

Marilynn Marchione can be followed at http://twitter.com/MMarchioneAP

Text Only | Photo Reprints
Bonus content
  • Silenced by Violence [Duplicate] Anti-violence youth gunned down, but not silenced FAYETTEVILLE, N.C. (AP) — Dressed in jeans, a low-neck T-shirt and white sneakers, 19-year-old Ravon Jordan strode confidently to the podium to address the city council. He had just three minutes, so he got right to the point: Eleven days earlier, on

    July 25, 2014 1 Photo

  • Arizona Execution Drugs [Duplicate] Execution offers evidence against lethal injection ST. LOUIS (AP) — The nation's third botched execution in six months offers more evidence for the courts that lethal injection carries too many risks and amounts to cruel and unusual punishment, death-row lawyers and other opponents said Thursday. De

    July 25, 2014 3 Photos

  • Teen Pilot-Crash [Duplicate] Family: Indiana teen pilot who crashed in ocean knew risks PLAINFIELD (AP) — Haris Suleman knew that flying around the world carried risks. But like adventurers before him, the 17-year-old pilot from Indiana also believed dreams aren't achieved without taking chances. "Why does any explorer undertake the nec

    July 24, 2014 1 Photo

  • Jamie Kennedy live in Kokomo this weekend Actor and stand-up comedian Jamie Kennedy said he's excited for his first-ever trip to the City of Firsts — a place he has heard only one thing about. He laughed Wednesday night, saying the only thing he's heard about Kokomo is that it's home to a pl

    July 24, 2014

  • Social Security Computer Woes [Duplicate] Social Security's $300M IT project doesn't work WASHINGTON (AP) — After spending nearly $300 million on a new computer system to handle disability claims, the Social Security Administration still can't get it to work. And officials can't say when it will. Six years ago, Social Security embarked on

    July 24, 2014 1 Photo

  • Awarded a Pell Grant? Better double-check WASHINGTON (AP) — Potentially tens of thousands of students awarded a Pell Grant or other need-based federal aid for the coming school year could find it taken away because of a mistake in filling out the form. The mistake primarily stems from an onl

    July 24, 2014

  • Film Review Lucy [Duplicate] Review: 'Lucy' won't stretch your brain capacity So let's start with the enticing premise of Luc Besson's "Lucy," starring Scarlett Johansson: Human beings only use 10 percent of their brain capacity. Imagine what it would be like if we could access all of it? Well, wow. It would be sort of like ..

    July 24, 2014 1 Photo

  • Arizona inmate dies 2 hours after execution began PHOENIX (AP) — A condemned Arizona inmate gasped for more than an hour and a half during his execution Wednesday before he died in an episode sure to add to the scrutiny surrounding the death penalty in the U.S. Arizona Attorney General Tom Horne's o

    July 24, 2014

  • Obama [Duplicate] Obama wants limits on US company mergers abroad LOS ANGELES (AP) — President Barack Obama is tapping into growing misgivings about tax-driven overseas mergers by U.S. corporations, issuing a new call to end the practice quickly and questioning the patriotism and citizenship of those companies. The

    July 24, 2014 1 Photo

  • Court rules prison agency mistreated former Pendleton counselor INDIANAPOLIS (AP) — A federal appeals court has ruled that Indiana's prison agency mistreated a female employee when it shrugged off her complaints about workers having sex on her desk and later fired her for having an affair with an official. The ap

    July 23, 2014

Latest news
Featured Ads
Only on our website
AP Video
Crashed Air Algerie Plane Found in Mali Israel Mulls Ceasefire Amid Gaza Offensive In Case of Fire, Oxygen Masks for Pets Mobile App Gives Tour of Battle of Atlanta Sites Anti-violence Advocate Killed, but Not Silenced. Dempsey: Putin May Light Fire and Lose Control Arizona Prison Chief: Execution Wasn't Botched Calif. Police Investigate Peacock Shooting Death Raw: Protesters, Soldiers Clash in West Bank Police: Doctor Who Shot Gunman 'Saved Lives' 'Modern Family' Star on Gay Athletes Coming Out MN Twins Debut Beer Vending Machine DA: Pa. Doctor Fired Back at Hospital Gunman Raw: Iowa Police Dash Cam Shows Wild Chase Obama Seeks Limits on US Company Mergers Abroad Large Family to Share NJ Lottery Winnings U.S. Flights to Israel Resume After Ban Lifted Official: Air Algerie Flight 'probably Crashed' TSA Administrator on Politics and Flight Bans Raw: National Guard Helps Battle WA Wildfires
Parade
Magazine

Click HERE to read all your Parade favorites including Hollywood Wire, Celebrity interviews and photo galleries, Food recipes and cooking tips, Games and lots more.
Obituaries
Poll
Kelly Lafferty's video on Tom Miller