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April 11, 2014

Researchers using math to whittle away at jet lag

WASHINGTON (AP) — Lots of apps claim they can help you fight jet lag. Now Michigan researchers say mathematical formulas suggest it's possible to adjust to new time zones a bit faster than previously thought, and they created their own free app to help.

Doctors have long said exposure to light is key. But how much, and when?

"If you get light in the wrong time or wrong way, it'll send you the wrong direction," said University of Michigan math professor Daniel Forger, who led the research published Thursday.

A master biological clock, called a circadian rhythm, regulates when we become sleepy and when we're more alert. Travel across time zones and the body clock has to reset itself.

Light is that clock's strongest regulator. In a study partly funded by the Air Force, the Michigan team used two equations proven to predict someone's circadian rhythm, and with computer modeling calculated different schedules of light exposure for more than 1,000 possible trips.

It's possible to customize a block of time each day when you should be in light, the brighter the better, and another when you should avoid it, Forger's team reported in the journal PLoS Computational Biology. (It didn't address other potential remedies such as melatonin.)

An example: Fly from Detroit to London, five hours ahead, arriving at 11 a.m. London time. Generally, it's thought to take a day per time zone to fully adjust. But the study suggests a three-day adjustment schedule, if you can stick with it: On the day after arrival, get light from 7:40 a.m. to 9 p.m.; from 6:20 a.m. to 7:40 p.m. on Day 2; and from 5 a.m. until 7:20 p.m. on Day 3.

A free iPhone app named Entrain does the calculations. Stay indoors, or stay up later, and it adjusts the advice.

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