Luck hit Wayne again for 19 yards on the next play, setting up a first-and-goal at the Seattle 3. Donald Brown took the football the rest of the way for the go-ahead score.
Luck completed a 2-point conversion pass across his body to Wayne in the middle of the end zone for a 31-28 lead, and Vinatieri added a 49-yard field goal with 1:55 left for the final margin.
Wilson had one final chance to pull out the comeback win. But he was hit hard by Jerrell Freeman on a fourth-and-15 attempt from his own 37-yard line, and the pass was intercepted by Darius Butler to seal the win with 1:23 to play.